Can Oriented Strand Board (OSB) be used interchangeably with plywood?

Yes. From section 9.1.3 of the NDS: The term “wood structural panel” refers to a wood-based panel product bonded with a waterproof adhesive. Included under this designation are plywood, OSB, and composite panels. The term “composite panel” refers to a wood structural panel comprised of wood veneer and reconstituted wood-based material and bonded with waterproof adhesive. The term OSB refers to a mat-formed wood structural panel comprised of thin rectangular wood stands arranged in cross-aligned layers with surface layers normally arranged in the long panel direction and bonded with waterproof adhesive. The term “plywood’ refers to a wood structural panel comprised of plies of wood veneer arranged in cross-aligned layers. The plies are bonded with an adhesive that cures on application of heat and pressure.

For additional information, contact the following organizations:

APA – THE ENGINEERED WOOD ASSOCIATION
7011 S. 19th Street
Tacoma, Washington 98466
253-565-6600
Fax: 253-565-7265
Website: http://www.apawood.org/

PFS-TECO
1507 Matt Pass
Cottage Grove, WI 53527
Phone: 608-839-1013
Website: https://www.pfsteco.com/